Prof. Kawauchi presented “Conditional expression and activation of DREADDs reveals novel impact of neuron-tumor communications on brain tumor progression” at Neuro2024 (Fukuoka). This is a collaborative study with Prof. Naofumi Uesaka from Tokyo Medical and Dental University, focusing on elucidating the relationship between brain tumors and neural activity. Now, the fields of brain tumors and neuroscience should be integrated, requiring more multifaceted analysis. On the other hand, such unique research is expected to reveal new mechanisms of tumor progression!

国立精神・神経医療研究センター神経研究所と名古屋市立大学大学院医学研究科から「プレスリリース：小児悪性脳腫瘍の進展に関わる鍵となる遺伝子を発見 -がん化にともなうゲノム構造変化の理解からの治療戦略づくり-」が公開されました。

With the opportunity provided by the Department of Neurophysiology at Tokyo Women’s Medical University (Professor Mariko Miyata), Professor Kawauchi presented his recent findings on brain tumor research and discussed future developments in the field. We extend our heartfelt gratitude to audience at Tokyo Women’s Medical University, Professor Mariko Miyata, and coordinator Dr. Hisako Nakayama for their participation and support.

With the opportunity provided by Professor Yoshiteru Arakawa, Prof. Kawauchi presented our research on ‘Understanding the (Epi)genome of Pediatric Brain Tumors Using Animal Models and Exploring Novel Therapies’ at Kyoto University Hospital. We hope this connection will foster future collaborative research!!

Professor Kawauchi’s project, ‘Identification of Novel Therapeutic Targets through the Development of Pediatric Brain Tumor Models Using Human ES Cell-Derived Brain Organoids,’ has been selected for the 2024 Kawano Pediatric Medical Scholarship Foundation Research Grant. This research aims to create pediatric brain tumor models from human ES cells and develop new therapies.

Dr. Kawauchi’s project, ‘Exploration of Therapeutic Target Molecules through Epigenomic Analysis of Medulloblastoma,’ has been awarded the 2023 Astellas Foundation for Research on Metabolic Disorders Research Grant. Over the next two years, we aim to elucidate the mechanisms that regulate the unique epigenome of medulloblastoma.

P.S.: With this support, our paper has been accepted by Developmental Cell. You can find the paper here.

川内教授が次世代がん医療加速化研究事業（P-PROMOTE）領域Aと領域Bにそれぞれ研究代表者および分担研究者（代表：TMDU上阪直史教授）として採択されました。
領域Aは脳腫瘍のエピゲノム研究、領域Bはがんと神経のコミュニケーションに関する研究です。
皆様よろしくお願い致します。

川内が東京医科歯科大学上阪直史教授との共同研究内容「Conditional expression and activation of DREADDs reveals novel impact of neuron-tumor communications on brain tumor progression」を Cancer Neuroscience Conference Heidelberg で口頭発表しました。
脳腫瘍と神経細胞のコミュニケーションの話です。興味がある方は是非ご連絡ください。